Bosewellic Acid

Bosewellic Acid

Boswellia, also known as Indian frankincense or Salai Guggal, is herbal Resin extract taken from the Boswellia Serrata tree.


Active Ingredients

• β-Boswellic acid (BA)
• Acetyl-β-Boswellic acid (ABA)
• 11-Keto-β-Boswellic acid (KBA)
• 3-O-Acetyl-11-Keto-β-Boswellic acid (AKBA)

Boswellic Acid upto 85%
AKBA upto 50%

Molecular Structure of Actives

Our Strict QC regime ensures all our Products & batches strictly adhere to our self- quality control test parameters and assay protocol standardized by HPLC. Heavy Metals and Microbiological profile meets IP standards. This ensure highest purity product reaches our customers.

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Anti-Cancer

  • Boswellia exhibits Anti – Cancer properties being potent inhibitor of angiogenesis and cell invasiveness. Boswellic acids induce Antiproliferation, differentiation, and apoptosis in Leukemia cell lines.
  • They exert cytotoxic effects on established human Glioblastoma and Leukemia cell lines, as well as on primary human meningioma cells.
  • Boswellic acids may help reduce Cerebral Edema in patients with brain tumours and in other cancer cell lines in vitro including breast, cervical, myeloma and Leukemia
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Osteoarthritis

  • Triterpenes present in AKBA reduce the synthesis of leukotrienes in intact neutrophils by inhibiting 5-LOX, the key enzyme involved in the biosynthesis of leukotrienes, which mediate inflammation.
  • AKBA impacts biomarkers of inflammation and arthritis such as TNFα, CRP, and IL-6 and inhibits MMP-3, an enzyme that breaks down cartilage, Collagen, and Connective tissue.
  • Boswellic Acid Suppresses pain and immobility associated with Osteoarthritis (OA).

Other health Benefits

  • Radiation Dermatitis
  • Ulcerative Colitis
  • Diabetes
  • Tendinopathy
  • Dysmenorrhea
  • Pharyngitis
health benefits

Pharmacological Activities of Boswellia Serrata

  • Cancer
    • Breast Cancer
    • Bladder Cancer
    • Brain Cancer
    • Cervical Cancer
    • Colon Cancer
    • Leukemia
    • Liver Cancer
    • Lung Cancer
    • Prostate Cancer
    • Pancreatic Cancer
  • Antioxidant
  • Melanoma
  • Renal Intestinal Fibrosis
  • Inflammatory Bowel Diseases (IBDs)
  • Diabetes
  • Central Nervous System Disorders
  • Ischemia-Reperfusion Injury (IRI)
  • Psoriasis

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References
1.J Ethnopharmacol. 2016 Sep 15;191:315-323. doi: 10.1016/j.jep.2016.06.053. Epub 2016.
2.Menon and Kar, 1971; Poeckel and Werz, 2006; Wildfeuer et al., 1998; Roy et al., 2005
3.Ammon et al., 1993, Wang et al. (2014), Banno et al., 2006, Wang et al., 2013
4.Hostanska et al., 2002; Roy et al., 2006

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